Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1525100 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL4163974 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL4809831 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL19552090 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL3634014 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL60574 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL19552101 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL996801 | 0.97 | ALDH1A1 (0.39) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL11086962 | 0.97 | ALDH1A1 (0.39) | ALDH1A1TSHRTP53L3MBTL1ACLY | |
| Trifluoroacetic Acid SCHEMBL4872786 | 0.94 | TSHR (0.37) | ALDH1A1TSHRTP53L3MBTL1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125642-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-06-20 | — | — | WO | disclosed |
| CN-115260211-B | Thiophene condensed ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2023227118-A1 | 3C-LIKE PROTEASE INHIBITOR | 广州国家实验室 | 2023-11-30 | — | — | WO | disclosed |
| CN-115260211-A | Thiophene fused ring containing derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-01 | — | — | CN | disclosed |
| US-10294199-B2 | Propyl cationic peptide lipids, synthesis method thereof, and application thereof | DALIAN NATIONALITIES UNIVERSITY (CN) | 2019-05-21 | — | — | US | disclosed |
| US-20170355667-A1 | PROPYL CATIONIC PEPTIDE LIPIDS, SYNTHESIS METHOD THEREOF, AND APPLICATION THEREOF | DALIAN NATIONALITIES UNIVERSITY (CN) | 2017-12-14 | — | — | US | disclosed |
| US-5089500-A | Viricides; hepatitis, aids | BURROUGHS WELLCOME CO. (US) | 1992-02-18 | — | — | US | disclosed |
| US-5034394-A | Therapeutic nucleosides | BURROUGHS WELLCOME CO. (US) | 1991-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355667-A1 | PROPYL CATIONIC PEPTIDE LIPIDS, SYNTHESIS METHOD THEREOF, AND APPLICATION THEREOF | PCNP, PLIN1, PLIN3 | ALDH1A1 4655/4885TSHR 1252/4885TP53 2534/4885 |
| US-10294199-B2 | Propyl cationic peptide lipids, synthesis method thereof, and application thereof | PCNP, PLIN1, PLIN3 | ALDH1A1 4655/4885TSHR 1252/4885TP53 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.