SCHEMBL9632142

SCHEMBL9632142

CCOC(C)OCC.O=Cc1cccc(Oc2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.49
MAOB P27338 3/20 0.49
EPOR P19235 3/20 0.47
PTGS1 P23219 3/20 0.46
TTR P02766 1/20 0.44
TLR4 O00206 1/20 0.43
TLR2 O60603 1/20 0.43
ALOX5 P09917 3/20 0.43
PTGS2 P35354 2/20 0.43
ALOX5AP P20292 1/20 0.43
PPARG P37231 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
SRC P12931 1/20 0.41
LMNA P02545 2/20 0.40
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
FFAR1 O14842 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25518732 0.85 MAOA (0.47) MAOAMAOBNPC1RAB9ATDP1
Benzaldehyde SCHEMBL367504 0.83 ALDH1A1 (0.54) MAOAMAOBPPARGNPC1LMNA
SCHEMBL29484309 0.83 MAOB (0.61) MAOAMAOBEPORPTGS1TTR
SCHEMBL11482497 0.83 MAOB (0.61) MAOAMAOBEPORPTGS1TTR
SCHEMBL98478 0.83 MAOB (0.61) MAOAMAOBEPORPTGS1TTR
Fluoride SCHEMBL27948206 0.81 MAOB (0.59) MAOAMAOBEPORPTGS1TTR
SCHEMBL11222905 0.81 MAOB (0.59) MAOAMAOBEPORPTGS1TTR
SCHEMBL3712082 0.80 TTR (0.52) MAOAMAOBTTRNPC1RAB9A
Benzaldehyde SCHEMBL11346796 0.80 ALDH1A1 (0.50) MAOAMAOBPPARGNPC1LMNA
SCHEMBL5806680 0.80 MAOB (0.57) MAOAMAOBEPORPTGS1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0289669-B1 PROCESS FOR PREPARING 3-PHENOXYBENZALDEHYDES HARDWICKE CHEMICAL COMPANY (US) 1992-04-01 EP claimed
EP-0289669-A1 Process for preparing 3-phenoxybenzaldehydes HARDWICKE CHEMICAL COMPANY (US) 1988-11-09 EP claimed
US-4691033-A Process for preparing 3-phenoxybenzaldehydes HARDWICKE CHEMICAL COMPANY (US) 1987-09-01 US claimed
EP-0289669-B1 PROCESS FOR PREPARING 3-PHENOXYBENZALDEHYDES HARDWICKE CHEMICAL COMPANY (US) 1992-04-01 EP disclosed
EP-0289669-A1 Process for preparing 3-phenoxybenzaldehydes HARDWICKE CHEMICAL COMPANY (US) 1988-11-09 EP disclosed
EP-0289669-A1 Process for preparing 3-phenoxybenzaldehydes HARDWICKE CHEMICAL COMPANY (US) 1988-11-09 EP disclosed
US-4691033-A Process for preparing 3-phenoxybenzaldehydes HARDWICKE CHEMICAL COMPANY (US) 1987-09-01 US disclosed
US-4691033-A Process for preparing 3-phenoxybenzaldehydes HARDWICKE CHEMICAL COMPANY (US) 1987-09-01 US disclosed