Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072982 | 0.96 | POLB (0.58) | POLBSMN1; SMN2 | |
| SCHEMBL140038 | 0.90 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6541474 | 0.87 | POLB (0.50) | POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4277213 | 0.85 | POLB (0.48) | POLBSMN1; SMN2 | |
| SCHEMBL4463389 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL506516 | 0.80 | HDAC3 (0.60) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL12487022 | 0.80 | CYP4A11 (0.59) | POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5073633 | 0.80 | MTNR1A (0.71) | — | |
| SCHEMBL3452433 | 0.79 | POLB (0.68) | POLBSMN1; SMN2 | |
| SCHEMBL4313502 | 0.79 | POLB (0.44) | POLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331943-B1 | PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |