Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 10/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | MPC2 | O95563 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727467 | 0.92 | CYP3A4 (0.52) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL9632033 | 0.89 | CYP3A4 (0.46) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL9630752 | 0.87 | CYP3A4 (0.48) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL10638937 | 0.86 | ALDH1A1 (0.55) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL10639115 | 0.85 | MEN1 (0.44) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL10636511 | 0.85 | CYP3A4 (0.47) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL9632682 | 0.84 | CYP3A4 (0.45) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL9632674 | 0.84 | CYP3A4 (0.45) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL10639191 | 0.84 | MEN1 (0.52) | CYP3A4MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL10642072 | 0.83 | CYP3A4 (0.52) | CYP3A4MEN1ALDH1A1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |