Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethylene Glycol SCHEMBL5411909 | 0.91 | ALDH1A1 (0.56) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL1362251 | 0.90 | TSHR (0.56) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL181725 | 0.90 | TSHR (0.56) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| Tetraethylene Glycol SCHEMBL3114276 | 0.87 | MEN1 (0.58) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| Triethylene Glycol SCHEMBL31176005 | 0.87 | MEN1 (0.58) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL28726903 | 0.87 | TSHR (0.53) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| 2-Ethoxyethanol SCHEMBL11662758 | 0.87 | ALDH1A1 (0.74) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| 2-Ethoxyethanol SCHEMBL1355783 | 0.87 | ALDH1A1 (0.74) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| 2-Ethoxyethanol SCHEMBL9187293 | 0.87 | ALDH1A1 (0.74) | ALDH1A1FFAR3TSHRMAPK1KMT2A | |
| 2-Ethoxyethanol SCHEMBL11589198 | 0.87 | ALDH1A1 (0.74) | ALDH1A1FFAR3TSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122603-A | PURIFIED INSULIN MEDIATORS AND PURIFICATION PROCESS FOR SAME | THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1992-06-16 | — | — | US | claimed |