Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 19/20 | 0.63 |
| ▸ | HRH1 | P35367 | 12/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875531 | 0.86 | HTR2A (0.63) | HTR2AHRH1HTR2CRET | |
| SCHEMBL4653844 | 0.84 | ANPEP (0.53) | HTR2AHRH1HTR2CRETHDAC4 | |
| SCHEMBL6112254 | 0.84 | ANPEP (0.53) | HTR2AHRH1HTR2CRETHDAC4 | |
| SCHEMBL24631299 | 0.83 | HTR2A (0.66) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL11526876 | 0.80 | HTR2A (0.40) | HTR2AHRH1HTR2CRET | |
| SCHEMBL8994177 | 0.78 | HTR2A (0.66) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL7003538 | 0.77 | HTR2A (1.00) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL29365726 | 0.77 | HTR2A (1.00) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL9331557 | 0.77 | HTR2A (0.43) | HTR2AHRH1HTR2CRET | |
| SCHEMBL8272136 | 0.75 | HTR2A (0.61) | HTR2AHRH1HTR2CHDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101059-A | Xanthene compounds | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| WO-1991008190-A1 | AMINO ACID PROTECTING GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-06-13 | — | — | WO | disclosed |
| US-4152356-A | SELECTIVE CARBONYLATION OF 9,10-DIHYDROANTHRACENE TO FORM 9-FORMYL-9,10-DIHYDROANTHRACENE | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-01 | — | — | US | disclosed |