SCHEMBL8272136

SCHEMBL8272136

OC1c2ccccc2Cc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 12/20 0.61
HRH1 P35367 8/20 0.54
HTR2C P28335 1/20 0.54
HDAC4 P56524 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC5 Q9UQL6 1/20 0.52
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
ANPEP P15144 2/20 0.46
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
CAMK2A Q9UQM7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7176437 0.86 HTR2A (0.58) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL6514594 0.84 ANPEP (0.59) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL7742080 0.84 ANPEP (0.59) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL506278 0.83 ACP3 (0.56) HTR2AMAOAMAOBCYP1A2CYP2D6
Fluorene SCHEMBL3661672 0.80 MAOA (0.48) HTR2AHRH1HTR2CHDAC4HDAC7
Fluorene SCHEMBL7203740 0.80 MAOA (0.48) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL2796781 0.80 HTR2A (0.42) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL30043804 0.80 HTR2A (0.42) HTR2AHRH1HTR2CHDAC4HDAC7
SCHEMBL21847059 0.79 CYP1A2 (0.62) HTR2AMAOAMAOBCYP1A2CYP2D6
SCHEMBL3628239 0.78 MAOA (0.60) HTR2AMAOAMAOBCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE32943-E SOLUBILIZING, STABILIZING HONSHU SEISHI KABUSHIKI KAISHA (JP) 1989-06-06 US claimed
US-4181565-A Process for cooking lignocellulosic material in the presence of hydroxyanthracenes and derivatives thereof HONSHU SEISHI KABUSHIKI KAISHA (JP) 1980-01-01 US claimed
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 US disclosed
US-9650357-B2 Reagent for enhancing generation of chemical species TOYO GOSEI CO., LTD. (JP) 2017-05-16 US disclosed
US-9618844-B2 Reagent and composition of resist TOYO GOSEI CO., LTD. (JP) 2017-04-11 US disclosed
US-9618844-B2 Reagent and composition of resist TOYO GOSEI CO., LTD. (JP) 2017-04-11 US disclosed
EP-2970811-B1 VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND A POLYAROMATIC HYDROCARBON CHEVRON ORONITE CO (US) 2017-01-25 EP disclosed
US-20160194300-A1 REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES OSAKA UNIVERSITY (JP) 2016-07-07 US disclosed
US-20160070165-A1 REAGENT AND COMPOSITION OF RESIST OSAKA UNIVERSITY (JP) 2016-03-10 US disclosed
US-20160070165-A1 REAGENT AND COMPOSITION OF RESIST OSAKA UNIVERSITY (JP) 2016-03-10 US disclosed
EP-2970811-A2 VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND A POLYAROMATIC HYDROCARBON Chevron Oronite Company LLC (US) 2016-01-20 EP disclosed
WO-2014149086-A2 VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND A POLYAROMATIC HYDROCARBON CHEVRON ORONITE COMPANY LLC (US) 2014-09-25 WO disclosed
US-20140274842-A1 VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND A POLYAROMATIC HYDROCARBON CHEVRON ORONITE COMPANY LLC (US) 2014-09-18 US disclosed
US-20130058980-A1 SMALL MOLECULE INHIBITORS OF PROTEIN KINASES LEVOLTA PHARMACEUTICALS, INC. 2013-03-07 US disclosed
US-20120322683-A1 ENZYMATIC SIGNAL GENERATION AND DETECTION OF BINDING COMPLEXES IN STATIONARY FLUIDIC CHIP INTEL CORPORATION 2012-12-20 US disclosed
US-20060084660-A1 Psychological disorders; analgesics; Parkinson's disease; antiepileptic agents; irritable bowel disorders; antiarrhythmia agents NEUROMED TECHNOLOGIES INC. 2006-04-20 US disclosed
CN-1750757-A Method of deterring birds from plant and structural surfaces ARKION LIFE SCIENCES LLC (US) 2006-03-22 CN disclosed
CN-1317929-A Product and method for improving avian health DCV INC (US) 2001-10-17 CN disclosed
US-RE32943-E SOLUBILIZING, STABILIZING HONSHU SEISHI KABUSHIKI KAISHA (JP) 1989-06-06 US disclosed
US-4181565-A Process for cooking lignocellulosic material in the presence of hydroxyanthracenes and derivatives thereof HONSHU SEISHI KABUSHIKI KAISHA (JP) 1980-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160194300-A1 REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES CYBB, PPOX, GPX4 HTR2A 4038/4885HRH1 686/4885HTR2C 4100/4885
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 HTR2A 2808/4885HRH1 4800/4885HTR2C 4095/4885
US-20060084660-A1 Psychological disorders; analgesics; Parkinson's disease; antiepileptic agents; irritable bowel disorders; antiarrhythmia agents CACNA1D, CACNA1E, CACNA1B HTR2A 167/4885HRH1 310/4885HTR2C 187/4885
US-20160070165-A1 REAGENT AND COMPOSITION OF RESIST ALAD, POLRMT, POLL HTR2A 4150/4885HRH1 476/4885HTR2C 4035/4885
US-20130058980-A1 SMALL MOLECULE INHIBITORS OF PROTEIN KINASES SYK, BTK, LCK HTR2A 4287/4885HRH1 2108/4885HTR2C 4179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.