SCHEMBL7003538

SCHEMBL7003538

NCC1c2ccccc2Cc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 18/20 1.00
HRH1 P35367 5/20 1.00
HTR2C P28335 3/20 1.00
RET P07949 1/20 0.76
SLC6A2 P23975 2/20 0.71
SLC6A4 P31645 2/20 0.71
DRD2 P14416 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365726 1.00 HTR2A (1.00) HTR2AHRH1HTR2CRETSLC6A2
SCHEMBL2244831 0.86 HTR2A (1.00) HTR2AHRH1HTR2CRETSLC6A2
Hydrochloric Acid SCHEMBL9084155 0.84 HTR2A (0.96) HTR2AHRH1HTR2CRETSLC6A2
SCHEMBL11879547 0.83 HTR2A (0.84) HTR2AHRH1HTR2CRETSLC6A2
SCHEMBL6997509 0.80 HTR2A (0.66) HTR2AHRH1HTR2CRETSLC6A2
SCHEMBL11678484 0.79 HTR2A (0.66) HTR2AHRH1HTR2CRETSLC6A2
SCHEMBL2941714 0.78 HTR2A (0.62) HTR2AHRH1HTR2CRETSLC6A2
SCHEMBL9632433 0.77 HTR2A (0.63) HTR2AHRH1HTR2CRETSLC6A2
SCHEMBL21996453 0.77 HTR2A (0.61) HTR2AHRH1HTR2CRETSLC6A2
SCHEMBL22049110 0.77 HTR2A (0.61) HTR2AHRH1HTR2CRETSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547250-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS Terran Biosciences Inc. (US) 2025-05-07 EP claimed
US-20250049748-A1 ANALOGS OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE TERRAN BIOSCIENCES INC (US) 2025-02-13 US claimed
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-06-20 US claimed
EP-4313030-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS Terran Biosciences, Inc. (US) 2024-02-07 EP claimed
WO-2024006984-A1 METHODS AND COMPOSITIONS RELATING TO CONTROLLING PSYCHEDELIC EFFECTS WITH SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2024-01-04 WO claimed
WO-2023115002-A1 ANALOGS OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE TERRAN BIOSCIENCES INC. (US) 2023-06-22 WO claimed
WO-2023107966-A1 SALT AND SOLID FORMS OF LYSERGIC ACID DIETHYLAMIDE (LSD) AND ANALOGS TERRAN BIOSCIENCES, INC. (US) 2023-06-15 WO claimed
WO-2022212854-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS TERRAN BIOSCIENCES INC. (US) 2022-10-06 WO claimed
US-11278549-B2 Method of treating obesity MCMASTER UNIVERSITY (CA) 2022-03-22 US claimed
US-20200352950-A1 Novel method of treating dystonia NEUROTOBE PHARMACEUTICALS INC. (KR) 2020-11-12 US claimed
EP-3718549-A1 NOVEL PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DYSTONIA Korea Advanced Institute of Science and Technology (KR) 2020-10-07 EP claimed
CN-111655265-A Novel pharmaceutical composition for the treatment of dystonia 韩国科学技术院 2020-09-11 CN claimed
US-20180318298-A1 Method of Treating Obesity MCMASTER UNIVERSITY (CA) 2018-11-08 US claimed
US-20260138985-A1 Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders TERRAN BIOSCIENCES INC (US) 2026-05-21 US disclosed
US-20260138948-A1 N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS TERRAN BIOSCIENCES INC (US) 2026-05-21 US disclosed
US-20260125345-A1 SALTS AND SOLID FORMS OF N-ETHYL-2-(5-FLUORO-1H-INDOL-3-YL)-N-METHYLETHAN-1-AMINE TERRAN BIOSCIENCES INC. 2026-05-07 US disclosed
WO-2014018563-A2 METHODS FOR THE TREATMENT OF CANCER THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2014-01-30 WO disclosed
EP-1069132-B1 Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them SERVIER LAB (FR) 2003-10-01 EP disclosed
US-6277851-B1 ORALLY ADMINISTERED TRYPSIN-RELATED SERINE PROTEASE INHIBITORS; ANTICOAGULANTS ADIR ET COMPAGNIE (FR) 2001-08-21 US disclosed
EP-1069132-A1 Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them ADIR ET COMPAGNIE (FR) 2001-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180318298-A1 Method of Treating Obesity GPR119, HTR2A, GIPR HTR2A 2/4885HRH1 685/4885HTR2C 20/4885
US-11278549-B2 Method of treating obesity GPR119, HTR2A, GIPR HTR2A 2/4885HRH1 685/4885HTR2C 20/4885
US-20260138948-A1 N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS HTR1D, HTR2C, TPH1 HTR2A 14/4885HRH1 402/4885HTR2C 2/4885
US-20260138985-A1 Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders TPH2, TPH1, HTR1D HTR2A 5/4885HRH1 1240/4885HTR2C 4/4885
US-20250049748-A1 ANALOGS OF 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE PNMT, HNMT, COMT HTR2A 37/4885HRH1 1408/4885HTR2C 5/4885
US-20240197681-A1 METHODS AND COMPOSITIONS RELATING TO PSYCHEDELICS AND SEROTONIN RECEPTOR MODULATORS HTR1A, HTR2A, HTR3A HTR2A 2/4885HRH1 575/4885HTR2C 5/4885
US-20260125345-A1 SALTS AND SOLID FORMS OF N-ETHYL-2-(5-FLUORO-1H-INDOL-3-YL)-N-METHYLETHAN-1-AMINE HTR1D, GRIN2D, SLC1A2 HTR2A 38/4885HRH1 3607/4885HTR2C 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.