Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19194891 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPK1SMN1; SMN2ENPP1HPGD | |
| SCHEMBL9677374 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPK1SMN1; SMN2ENPP1HPGD | |
| SCHEMBL272835 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPK1SMN1; SMN2ENPP1HPGD | |
| SCHEMBL13140144 | 0.76 | HSD17B10 (0.41) | ALDH1A1MAPK1HPGDKDM4EGAA | |
| SCHEMBL7103183 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPK1SMN1; SMN2ENPP1HPGD | |
| SCHEMBL10725249 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPK1SMN1; SMN2ENPP1HPGD | |
| SCHEMBL5164814 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MAPK1SMN1; SMN2ENPP1HPGD | |
| SCHEMBL8421909 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MAPK1SMN1; SMN2ENPP1HPGD | |
| SCHEMBL19194460 | 0.72 | EGLN2 (0.55) | ALDH1A1MAPK1ENPP1HPGDKDM4E | |
| SCHEMBL5983773 | 0.72 | KDM1A (0.44) | ALDH1A1MAPK1SMN1; SMN2ENPP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257515-B1 | METHOD FOR HARDENING LAYERS CONTAINING A PROTEIN BINDER | Agfa-Gevaert AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| US-5028519-A | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0257515-A2 | Method for hardening layers containing a protein binder | Agfa-Gevaert AG (DE) | 1988-03-02 | — | — | EP | disclosed |