Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.51 |
| ▸ | FABP7 | O15540 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15981181 | 0.88 | KMT2A (0.58) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL10937196 | 0.86 | FABP5 (0.46) | KMT2AFABP5FABP7EPHX2ALDH1A1 | |
| SCHEMBL648282 | 0.84 | KMT2A (0.49) | KMT2AFABP5FABP7EPHX2ALDH1A1 | |
| SCHEMBL10405601 | 0.83 | FABP5 (0.56) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL30253705 | 0.83 | FABP5 (0.52) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL13140300 | 0.81 | EPHX2 (0.47) | KMT2AFABP5FABP7EPHX2ALDH1A1 | |
| SCHEMBL44677 | 0.80 | FABP5 (0.59) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL29381061 | 0.80 | FABP5 (0.59) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL29901230 | 0.80 | FABP5 (0.59) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL15982314 | 0.80 | KMT2A (0.48) | KMT2AFABP5FABP7EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161202-A1 | Novel strategy for selective regulation of background surface property in microarray fabrication and method to eliminated self quenching in micro arrays | INTEL CORPORATION | 2008-07-03 | — | — | US | claimed |
| US-10273539-B2 | Methods of using nucleotide analogues | QIAGEN SCIENCES, LLC (US) | 2019-04-30 | — | — | US | disclosed |
| US-9725474-B2 | Modified nucleic acid | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-08-08 | — | — | US | disclosed |
| US-20160016983-A1 | New Modified Nucleic Acid | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016983-A1 | New Modified Nucleic Acid | RNGTT, RNASEH1, RNASE1 | KMT2A 839/4885FABP5 802/4885FABP7 925/4885 |
| US-10273539-B2 | Methods of using nucleotide analogues | NT5C3B, SAMHD1, RNGTT | KMT2A 2787/4885FABP5 4646/4885FABP7 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.