SCHEMBL9632744

SCHEMBL9632744

CCOC(=O)C(C)Oc1ccc(Oc2cnc3ccc(Cl)cc3n2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.74
ALDH1A1 P00352 5/20 0.74
LMNA P02545 4/20 0.74
CYP1A2 P05177 4/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
HPGD P15428 2/20 0.74
CYP3A4 P08684 2/20 0.74
TP53 P04637 1/20 0.74
ALOX15 P16050 1/20 0.74
NFKB1 P19838 1/20 0.74
HIF1A Q16665 1/20 0.74
GMNN O75496 1/20 0.74
APEX1 P27695 1/20 0.74
PMP22 Q01453 1/20 0.74
NPSR1 Q6W5P4 1/20 0.74
L3MBTL1 Q9Y468 4/20 0.49
HTT P42858 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
GAA P10253 1/20 0.46
EPHX2 P34913 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quizalofop-P-Ethyl SCHEMBL29474422 0.96 MAPT (0.67) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
Quizalofop-P-Ethyl SCHEMBL53466 0.96 MAPT (0.67) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL9139248 0.96 MAPT (0.67) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL30406 0.96 MAPT (0.67) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
Quizalofop-P-Ethyl SCHEMBL23045019 0.95 MAPT (0.66) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL23045020 0.95 MAPT (0.66) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL8537282 0.92 CYP1A2 (0.63) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL27358324 0.89 ALDH1A1 (0.60) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
SCHEMBL8880041 0.89 MAPT (0.77) MAPTALDH1A1LMNACYP1A2SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL28275986 0.89 MAPT (0.59) MAPTALDH1A1LMNACYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268554-B1 1,5-DIPHENYL PYRAZOLE-3-CARBONIC-ACID DERIVATIVES FOR THE PROTECTION OF CULTURED PLANTS CIBA-GEIGY AG (CH) 1991-12-27 EP claimed
US-5114462-A Herbicides as plant growth regulators, phenoxypropionic acid esters and derivatives CIBA-GEIGY CORPORATION (US) 1992-05-19 US disclosed
US-4944790-A PLANT SAFENING AGENTS FOR USE WITH CERTAIN HERBICIDES CIBA-GEIGY CORPORATION (US) 1990-07-31 US disclosed