Quizalofop Ethyl Ester

Quizalofop Ethyl Ester

SCHEMBL8537282

CC(Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1)C(=O)O.CCOC(=O)C(C)Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1

nearest known ligand 0.63

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.63
LMNA P02545 2/20 0.63
MAPT P10636 2/20 0.63
ALDH1A1 P00352 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
TP53 P04637 1/20 0.63
CYP3A4 P08684 1/20 0.63
ALOX15 P16050 1/20 0.63
NFKB1 P19838 1/20 0.63
HIF1A Q16665 1/20 0.63
GMNN O75496 1/20 0.63
HPGD P15428 1/20 0.63
APEX1 P27695 1/20 0.63
PMP22 Q01453 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
L3MBTL1 Q9Y468 4/20 0.46
GAA P10253 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTT P42858 1/20 0.43
MAP4K4 O95819 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quizalofop-P-Ethyl SCHEMBL29474422 0.96 MAPT (0.67) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL9139248 0.96 MAPT (0.67) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
Quizalofop-P-Ethyl SCHEMBL53466 0.96 MAPT (0.67) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL30406 0.96 MAPT (0.67) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
Quizalofop-P-Ethyl SCHEMBL23045019 0.95 MAPT (0.66) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
Quizalofop Ethyl Ester SCHEMBL23045020 0.95 MAPT (0.66) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
Quizalofop SCHEMBL9540398 0.92 CYP1A2 (0.61) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
SCHEMBL9632744 0.92 MAPT (0.74) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
Quizalofop SCHEMBL111413 0.92 ALDH1A1 (0.72) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2
Quizalofop SCHEMBL29763487 0.92 ALDH1A1 (0.72) CYP1A2LMNAMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed