SCHEMBL9632783

SCHEMBL9632783

CC(C)(C)OC(=O)[C@H](CCC(N)=O)NC(=O)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.47
ACE P12821 1/20 0.46
POLB P06746 2/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CNR2 P34972 4/20 0.44
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
ITGA4 P13612 1/20 0.43
ITGB7 P26010 1/20 0.43
REN P00797 1/20 0.43
KLK5 Q9Y337 1/20 0.43
MAPT P10636 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
CTSS P25774 1/20 0.43
PSMB8 P28062 1/20 0.42
PSMB5 P28074 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9632782 1.00 LTA4H (0.47) LTA4HACEPOLBMEN1KMT2A
SCHEMBL7290254 0.84 CTSK (0.54) CTSLCTSBCTSS
SCHEMBL11780835 0.83 SMN1; SMN2 (0.49) LTA4HKLK5MAPT
SCHEMBL20158413 0.82 POLB (0.51) POLBMEN1KMT2ACNR2ALDH1A1
SCHEMBL236526 0.82 KMT2A (0.58) POLBKMT2ACNR2CTSLCTSB
SCHEMBL26109837 0.82 CNR2 (0.53) POLBMEN1KMT2ACNR2ALDH1A1
SCHEMBL6249937 0.82 KMT2A (0.58) POLBKMT2ACNR2CTSLCTSB
SCHEMBL236527 0.82 KMT2A (0.58) POLBKMT2ACNR2CTSLCTSB
SCHEMBL6249941 0.82 KMT2A (0.58) POLBKMT2ACNR2CTSLCTSB
SCHEMBL26109839 0.82 CNR2 (0.53) POLBMEN1KMT2ACNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5105007-A Fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1992-04-14 US disclosed
US-5100807-A Fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1992-03-31 US disclosed
EP-0312898-A2 Phenylacetylglutamine (pag) analytical test ABBOTT LABORATORIES (US) 1989-04-26 EP disclosed