Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306356 | 0.90 | TSHR (0.50) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL29550931 | 0.82 | TSHR (0.52) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL609984 | 0.82 | KDM4E (0.54) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL422881 | 0.82 | TSHR (0.52) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9632261 | 0.80 | NNMT (0.46) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL11993072 | 0.79 | SMN1; SMN2 (0.39) | CA12CA9ALDH1A1LMNAMAPT | |
| SCHEMBL510186 | 0.79 | ALDH1A1 (0.51) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL9630374 | 0.79 | TSHR (0.49) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL4162744 | 0.79 | KDM4E (0.48) | TSHRCYP1A2ALDH1A1LMNAMAPT | |
| SCHEMBL4154574 | 0.79 | ALDH1A1 (0.57) | CYP1A2ALDH1A1LMNAMAPTTARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098462-A | Herbicides | SANDOZ LTD. (CH) | 1992-03-24 | — | — | US | disclosed |
| US-5098466-A | Herbicides | SANDOZ LTD. (CH) | 1992-03-24 | — | — | US | disclosed |