Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.73 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.72 |
| ▸ | WNT3A | P56704 | 5/20 | 0.72 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.68 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28751191 | 0.92 | GABRA1 (0.81) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL1563151 | 0.91 | GABRA1 (0.74) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8959575 | 0.89 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8959628 | 0.89 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8959954 | 0.89 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8960008 | 0.89 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8077164 | 0.89 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8959866 | 0.89 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8960031 | 0.89 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL10498633 | 0.89 | GABRA1 (0.86) | ADAM17CTNNB1WNT3AGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089497-A | Dopaminergic agents | WARNER-LAMBERT COMPANY (US) | 1992-02-18 | — | — | US | disclosed |