Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.72 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.63 |
| ▸ | WNT3A | P56704 | 5/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959954 | 1.00 | GABRA1 (0.72) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL8960031 | 1.00 | GABRA1 (0.72) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL8077164 | 1.00 | GABRA1 (0.72) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL8959575 | 1.00 | GABRA1 (0.72) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL8959866 | 1.00 | GABRA1 (0.72) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL8960008 | 1.00 | GABRA1 (0.72) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL1563151 | 0.98 | GABRA1 (0.74) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL28751191 | 0.94 | GABRA1 (0.81) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL9633079 | 0.89 | ADAM17 (0.73) | GABRA1GABRB2MAPTCYP1A2CYP2D6 | |
| SCHEMBL8959835 | 0.88 | GABRA1 (0.64) | GABRA1GABRB2MAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530019-A | FOR TREATMENT OF PROSTATE GLAND DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |