Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591441 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PAOXMEN1KMT2ANPSR1 | |
| SCHEMBL21999366 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PAOXMEN1KMT2ANPSR1 | |
| SCHEMBL21998731 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PAOXMEN1KMT2ANPSR1 | |
| SCHEMBL21999365 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PAOXMEN1KMT2ANPSR1 | |
| SCHEMBL9544143 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PAOXMEN1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL29729374 | 0.99 | ALDH1A1 (0.59) | ALDH1A1PAOXMEN1KMT2ANPSR1 | |
| SCHEMBL7158304 | 0.94 | ALDH1A1 (0.63) | ALDH1A1PAOXMEN1KMT2ANPSR1 | |
| SCHEMBL9633498 | 0.93 | FAAH (0.55) | ALDH1A1PAOXMEN1KMT2AFAAH | |
| SCHEMBL26393724 | 0.93 | FAAH (0.55) | ALDH1A1PAOXMEN1KMT2AFAAH | |
| Lactic Acid SCHEMBL6314994 | 0.91 | ALDH1A1 (0.53) | ALDH1A1PAOXMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |