Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 7/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.53 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587622 | 0.91 | FAAH (0.56) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL9633433 | 0.83 | FAAH (0.48) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL18596712 | 0.82 | FAAH (0.61) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL9371834 | 0.82 | FAAH (0.61) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL9368530 | 0.82 | FAAH (0.61) | NAAAFAAHDNM1SELPCNR1 | |
| Ethylene Glycol SCHEMBL9622565 | 0.82 | NAAA (0.71) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL6399330 | 0.81 | FAAH (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL8640203 | 0.81 | FAAH (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL27985151 | 0.80 | FAAH (0.57) | NAAAFAAHDNM1CNR1MEN1 | |
| SCHEMBL25008200 | 0.80 | FAAH (0.77) | NAAAFAAHDNM1SELPCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |