Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10582246 | 0.94 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL29361952 | 0.94 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8115453 | 0.91 | MEN1 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8108773 | 0.91 | MEN1 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL26801512 | 0.91 | MEN1 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8101448 | 0.91 | MEN1 (0.49) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL9633149 | 0.89 | LMNA (0.48) | MEN1KMT2ALMNATSHRZDHHC20 | |
| SCHEMBL6751434 | 0.88 | MEN1 (0.54) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL6751402 | 0.88 | MEN1 (0.54) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL6751392 | 0.88 | MEN1 (0.54) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |