Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19031932 | 0.90 | PRCP (0.42) | PRCPSLC22A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL24639493 | 0.75 | PRCP (0.42) | PRCPSLC22A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL1206939 | 0.75 | PRCP (0.42) | PRCPSLC22A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL24639478 | 0.75 | PRCP (0.42) | PRCPSLC22A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL30101476 | 0.75 | PRCP (0.42) | PRCPSLC22A1CYP2D6CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL30531541 | 0.74 | PRCP (0.41) | PRCPSLC22A1CYP2D6CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL21519256 | 0.74 | PRCP (0.41) | PRCPSLC22A1CYP2D6CYP3A4KDM4E | |
| SCHEMBL3111967 | 0.73 | PRCP (0.43) | PRCPSLC22A1CYP2D6MEN1CYP3A4 | |
| SCHEMBL31062465 | 0.73 | HRH3 (0.41) | PRCPSLC22A1HTR2C | |
| SCHEMBL9635463 | 0.72 | HTR6 (0.46) | GBA1KDM1AKDM1BHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096900-A | Antidepressants, anxiolytic agents | SYNTHELABO (FR) | 1992-03-17 | — | — | US | disclosed |
| US-5081128-A | Antidepressants, anxiolytic agents | SYNTHELABO (FR) | 1992-01-14 | — | — | US | disclosed |