Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228929 | 0.89 | MAOA (0.48) | HTR6KDM1AKDM1BMTNR1AMTNR1B | |
| SCHEMBL11228576 | 0.85 | MTNR1A (0.48) | HTR6GBA1KDM1AKDM1BMTNR1A | |
| Hydrochloric Acid SCHEMBL11232682 | 0.84 | MTNR1A (0.47) | HTR6GBA1KDM1AKDM1BHTR2C | |
| SCHEMBL11232133 | 0.83 | BCHE (0.48) | HTR6MTNR1AMTNR1BSLC6A4BCHE | |
| Hydrochloric Acid SCHEMBL11229034 | 0.81 | BCHE (0.47) | HTR6KDM1AKDM1BMTNR1AMTNR1B | |
| SCHEMBL4924943 | 0.79 | HTR2C (0.54) | HTR2CHTR2AHTR2B | |
| SCHEMBL9635410 | 0.78 | KDM1A (0.39) | GBA1KDM1AKDM1BHTR2CSLC6A4 | |
| SCHEMBL11235378 | 0.78 | KDM1A (0.43) | KDM1AHTR2CHTR2AHTR2BSLC6A4 | |
| SCHEMBL11231388 | 0.78 | HTR2C (0.52) | KDM1AHTR2CHTR2AHTR2BSLC6A4 | |
| Hydrochloric Acid SCHEMBL11231689 | 0.77 | KDM1A (0.43) | KDM1AHTR2CHTR2AHTR2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |