Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757141 | 0.88 | CYP19A1 (0.51) | CYP19A1CYP3A4CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL9633309 | 0.74 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL9367361 | 0.72 | CYP19A1 (0.69) | CYP19A1CYP3A4CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL9634666 | 0.71 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2CYP2D6TBXAS1 | |
| SCHEMBL27277223 | 0.69 | CYP19A1 (0.51) | CYP19A1CYP3A4CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL10859057 | 0.69 | CYP19A1 (0.43) | CYP19A1POLB | |
| SCHEMBL2818075 | 0.69 | CYP19A1 (0.50) | CYP19A1TBXAS1MEN1KMT2ACYP17A1 | |
| SCHEMBL966690 | 0.68 | CYP17A1 (0.59) | CYP19A1CYP11B1CYP11B2TBXAS1IDO1 | |
| SCHEMBL28065635 | 0.67 | CYP19A1 (0.49) | CYP19A1CYP17A1 | |
| SCHEMBL27626734 | 0.67 | CYP19A1 (0.49) | CYP19A1CYP3A4CYP11B1CYP11B2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691998-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-04-08 | — | — | US | disclosed |
| US-20130190508-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-20130190508-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-20130190508-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-8455661-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455661-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455661-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | NDC1, NBAS, NIT2 | CYP19A1 1033/4885CYP3A4 312/4885CYP11B1 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.