Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452908 | 0.98 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL30645420 | 0.98 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL9347454 | 0.96 | KMT2A (0.48) | NPC1RAB9AMEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL4353079 | 0.96 | NPC1 (0.48) | NPC1RAB9AMEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL28201693 | 0.94 | KMT2A (0.47) | NPC1RAB9AMEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL30688272 | 0.94 | CTSL (0.49) | NPC1RAB9AMEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL28869036 | 0.94 | CTSL (0.49) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL3506845 | 0.94 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AACHE | |
| Bicarbonate SCHEMBL4200785 | 0.90 | ALDH1A1 (0.49) | NPC1RAB9AMEN1KMT2AACHE | |
| SCHEMBL31742513 | 0.86 | ALDH1A1 (0.45) | NPC1RAB9AMEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
| EP-0485419-A1 | ACRIDINE DERIVATIVES | Trifree Limited (GB) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001974-A1 | ACRIDINE DERIVATIVES | TRIFREE LIMITED (GB) | 1991-02-21 | — | — | WO | disclosed |