Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728785 | 0.81 | CYP2D6 (0.49) | SIGMAR1MAPTCYP2D6TSHR | |
| SCHEMBL26934004 | 0.71 | OPRL1 (0.48) | — | |
| SCHEMBL3390865 | 0.71 | — | — | |
| SCHEMBL8707784 | 0.68 | KDM4E (0.51) | CYP2D6 | |
| SCHEMBL9633577 | 0.68 | TACR1 (0.46) | SIGMAR1HTR2A | |
| SCHEMBL14046960 | 0.67 | CYP2D6 (0.48) | SIGMAR1MAPTCYP2D6TSHR | |
| SCHEMBL10212375 | 0.65 | ALDH1A1 (0.58) | SIGMAR1HTR2A | |
| SCHEMBL735709 | 0.65 | SIGMAR1 (0.47) | SIGMAR1HTR2ACYP2D6 | |
| SCHEMBL17706256 | 0.65 | MC4R (0.56) | SIGMAR1HTR2A | |
| SCHEMBL11261994 | 0.64 | ALDH1A1 (0.61) | SIGMAR1HTR2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100903-A | Analgesics | ANAQUEST, INC. (US) | 1992-03-31 | — | — | US | disclosed |