Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505771 | 0.74 | HTT (0.53) | GRM2ALDH1A1POLBHSD17B10TACR1 | |
| SCHEMBL9767014 | 0.74 | GRM2 (0.51) | GRM2ALDH1A1POLBRAB9AHTR2A | |
| SCHEMBL9633705 | 0.73 | MC4R (0.46) | GRM2TACR1KCNH2 | |
| SCHEMBL4332334 | 0.69 | GRM2 (0.58) | GRM2ALDH1A1POLBRAB9AHTR2A | |
| SCHEMBL4096799 | 0.69 | GRM2 (0.58) | GRM2ALDH1A1POLBRAB9AHTR2A | |
| SCHEMBL4332336 | 0.69 | GRM2 (0.58) | GRM2ALDH1A1POLBRAB9AHTR2A | |
| SCHEMBL8325711 | 0.68 | GRM2 (0.54) | GRM2ALDH1A1POLBHSD17B10RAB9A | |
| SCHEMBL9456965 | 0.68 | HTT (0.51) | GRM2ALDH1A1POLBHSD17B10TACR1 | |
| SCHEMBL10085217 | 0.66 | HRH3 (0.71) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL18805034 | 0.66 | HRH3 (0.71) | ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149808-A | Nootropics, antihypoxic agents | BOEHRINGER INGELHEIM KG (DE) | 1992-09-22 | — | — | US | disclosed |
| US-5073671-A | Nootropic and antihypoxic agents | BOEHRINGER INGELHEIM KG (DE) | 1991-12-17 | — | — | US | disclosed |
| US-4833140-A | ANTIHYPOXIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1989-05-23 | — | — | US | disclosed |
| US-4767759-A | ANTIHYPOXICS | BOEHRINGER INGELHEIM KG (DE) | 1988-08-30 | — | — | US | disclosed |