Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484174 | 0.76 | HPGD (0.47) | HPGDMAPTPREPCACNA1GCACNA1H | |
| SCHEMBL9766998 | 0.75 | HPGD (0.46) | HPGDPREPCACNA1GCACNA1HCACNA1I | |
| SCHEMBL10503567 | 0.74 | HPGD (0.54) | MC4RHPGDKDM4ETP53MAPT | |
| SCHEMBL3201687 | 0.74 | DPP4 (0.50) | HPGDPREPCACNA1GCACNA1HCACNA1I | |
| SCHEMBL27623771 | 0.74 | BRD4 (0.47) | HPGDPREPCACNA1GCACNA1HCACNA1I | |
| SCHEMBL3201676 | 0.74 | DPP4 (0.50) | HPGDPREPCACNA1GCACNA1HCACNA1I | |
| SCHEMBL3185962 | 0.74 | DPP4 (0.50) | HPGDPREPCACNA1GCACNA1HCACNA1I | |
| SCHEMBL9633644 | 0.73 | GRM2 (0.47) | KCNH2TACR1GRM2 | |
| SCHEMBL9634058 | 0.73 | CYP19A1 (0.42) | HPGDMAPTPREPCACNA1GCACNA1H | |
| SCHEMBL9803156 | 0.71 | HPGD (0.43) | HPGDPREPCACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149808-A | Nootropics, antihypoxic agents | BOEHRINGER INGELHEIM KG (DE) | 1992-09-22 | — | — | US | disclosed |
| US-5073671-A | Nootropic and antihypoxic agents | BOEHRINGER INGELHEIM KG (DE) | 1991-12-17 | — | — | US | disclosed |
| US-4833140-A | ANTIHYPOXIC AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1989-05-23 | — | — | US | disclosed |
| US-4767759-A | ANTIHYPOXICS | BOEHRINGER INGELHEIM KG (DE) | 1988-08-30 | — | — | US | disclosed |