Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 12/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633815 | 0.93 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1 | |
| SCHEMBL9633734 | 0.84 | CYSLTR1 (0.73) | CYSLTR2CYSLTR1 | |
| SCHEMBL8951494 | 0.83 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1NAMPT | |
| SCHEMBL8951243 | 0.83 | CYSLTR1 (0.71) | CYSLTR2CYSLTR1 | |
| SCHEMBL8951199 | 0.82 | CYSLTR2 (0.87) | CYSLTR2CYSLTR1 | |
| SCHEMBL8951488 | 0.80 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1 | |
| SCHEMBL8951448 | 0.79 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1 | |
| SCHEMBL9634205 | 0.79 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1NAMPT | |
| SCHEMBL8951232 | 0.79 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1 | |
| SCHEMBL8998286 | 0.78 | EPHX2 (0.56) | CYSLTR2CYSLTR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337765-B1 | ACYLSULFONAMIDE DERIVATIVES OF ALPHA-CARBOCYCLYLTOLUIC ACIDS USED AS LEUKOTRIENE ANTAGONISTS | ICI AMERICAS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0337765-A2 | Acylsulfonamide derivatives of alpha-carbocyclyltoluic acids used as leukotriene antagonists | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |