Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751140 | 0.88 | BAZ2B (0.55) | SMN1; SMN2GAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22336206 | 0.85 | MAPT (0.68) | BAZ1AMAPTPBRM1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29538540 | 0.80 | BAZ2B (0.63) | BAZ1AMAPTPBRM1SMN1; SMN2CYP1A2 | |
| SCHEMBL5442167 | 0.80 | BAZ2B (0.63) | BAZ1AMAPTPBRM1SMN1; SMN2CYP1A2 | |
| SCHEMBL14175929 | 0.79 | BAZ2B (0.68) | BAZ2B | |
| SCHEMBL1825223 | 0.77 | GPR119 (0.45) | NPY5RMAPTSMN1; SMN2GAACYP1A2 | |
| SCHEMBL26332997 | 0.76 | BAZ1A (0.51) | BAZ1APBRM1USP7BAZ2B | |
| SCHEMBL2303295 | 0.74 | KDM4E (0.35) | PBRM1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL15661603 | 0.72 | BAZ2B (0.57) | BAZ1AMAPTSMN1; SMN2GAAMEN1 | |
| SCHEMBL22920036 | 0.72 | SMN1; SMN2 (0.49) | NPY5RMAPTSMN1; SMN2GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337765-B1 | ACYLSULFONAMIDE DERIVATIVES OF ALPHA-CARBOCYCLYLTOLUIC ACIDS USED AS LEUKOTRIENE ANTAGONISTS | ICI AMERICAS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0337765-A2 | Acylsulfonamide derivatives of alpha-carbocyclyltoluic acids used as leukotriene antagonists | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |