Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.67 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471191 | 1.00 | GNAI3 (0.67) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL23471439 | 0.98 | L3MBTL1 (0.69) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL4554866 | 0.93 | L3MBTL1 (0.69) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL9634169 | 0.93 | L3MBTL1 (0.69) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL12141609 | 0.92 | L3MBTL1 (0.60) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL8972823 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL4450061 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL1045855 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL7060548 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1TDP1MEN1 | |
| SCHEMBL8972980 | 0.90 | L3MBTL1 (0.80) | GNAI3GNAI1L3MBTL1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |