SCHEMBL9634019

SCHEMBL9634019

N=C1NC(=N)c2cc3cc(Cl)ccc3cc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.46
F11 P03951 1/20 0.37
AHR P35869 2/20 0.36
F7 P08709 2/20 0.36
F3 P13726 2/20 0.36
CMA1 P23946 1/20 0.36
LTA4H P09960 1/20 0.36
NR4A2 P43354 1/20 0.36
PPOX P50336 1/20 0.36
NOS1 P29475 2/20 0.34
DYRK1A Q13627 2/20 0.34
CES1 P23141 2/20 0.33
TGM2 P21980 1/20 0.33
CHEK1 O14757 1/20 0.32
DAPK3 O43293 1/20 0.32
MAP4K4 O95819 1/20 0.32
RET P07949 1/20 0.32
PIM1 P11309 1/20 0.32
LTK P29376 1/20 0.32
GRK5 P34947 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5439659 0.80 PPOX (0.50) AHRF7F3PPOXDYRK1A
SCHEMBL3229744 0.76 ALDH1A1 (0.41) CYP2A6ACHENOX1TP53KDM4E
SCHEMBL7583854 0.75 CYP2A6 (0.46) CYP2A6AHRNR4A2NOS1DYRK1A
SCHEMBL3218707 0.75 ALDH1A1 (0.43) CYP2A6NOX1TP53KDM4EKMT2A
SCHEMBL4288341 0.74 CYP2A6 (0.68) CYP2A6F11AHRF7F3
SCHEMBL11626337 0.74 CYP2A6 (0.68) CYP2A6F11AHRF7F3
SCHEMBL27765004 0.74 CYP2A6 (0.68) CYP2A6F11AHRF7F3
SCHEMBL11302716 0.74 CYP2A6 (0.68) CYP2A6F11AHRF7F3
SCHEMBL31665941 0.74 CYP2A6 (0.68) CYP2A6F11AHRF7F3
SCHEMBL865990 0.74 CYP2A6 (0.77) CYP2A6F11AHRF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3182563-A None JP disclosed
EP-0191215-B1 MEDIA FOR OPTICAL INFORMATION STORAGE COMPRISING AN ORGANIC MACROCYCLIC CHROMOPHORE SUBSTITUTED WITH A FILM CONFERRING ORGANIC SUBSTITUENT CELANESE CORPORATION (US) 1992-05-27 EP disclosed
US-5059510-A Media for optical information storage comprising an organic macrocyclic chromophore substituted with a film conferring organic substituent HOECHST CELANESE CORP. (US) 1991-10-22 US disclosed
JP-H03182563-A AZAANNULENE COMPOUND RICOH CO LTD 1991-08-08 JP disclosed
EP-0191970-B1 RECORDING INFORMATION MEDIA COMPRISING CHROMOPHORES CELANESE CORPORATION (US) 1989-09-20 EP disclosed
US-4725525-A Recording information media comprising chromophores HOEBBST CELANESE CORPORATION (US) 1988-02-16 US disclosed
EP-0191970-A1 Recording information media comprising chromophores CELANESE CORPORATION (US) 1986-08-27 EP disclosed
EP-0191215-A2 Media for optical information storage comprising an organic macrocyclic chromophore substituted with a film conferring organic substituent CELANESE CORPORATION (US) 1986-08-20 EP disclosed