Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.64 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.64 |
| ▸ | STS | P08842 | 4/20 | 0.64 |
| ▸ | ESR1 | P03372 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.64 |
| ▸ | SHBG | P04278 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL10335838 | 1.00 | MEN1 (0.70) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL11687810 | 0.97 | MEN1 (0.74) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL29198757 | 0.97 | MEN1 (0.74) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL15971654 | 0.97 | MEN1 (0.74) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL11692049 | 0.97 | MEN1 (0.74) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL5681977 | 0.87 | AKR1C3 (0.79) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL9634078 | 0.87 | LMNA (0.66) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL10531128 | 0.87 | LMNA (0.66) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL13930476 | 0.85 | HSD17B10 (0.70) | MEN1KMT2AHSD17B10AKR1C3TSHR | |
| SCHEMBL14569770 | 0.85 | HSD17B10 (0.70) | MEN1KMT2AHSD17B10AKR1C3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356454-B1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5001234-A | Cyclic hydrocarbons with an aminoalkyl sidechain | THE UPJOHN COMPANY (US) | 1991-03-19 | — | — | US | disclosed |