Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 6/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531128 | 1.00 | LMNA (0.66) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL8776090 | 0.89 | AKR1C3 (0.79) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11101736 | 0.88 | HSD17B1 (0.67) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL9746964 | 0.87 | HSD17B1 (0.66) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| Methoxymethane SCHEMBL10335838 | 0.87 | MEN1 (0.70) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| Methoxymethane SCHEMBL9634076 | 0.87 | MEN1 (0.70) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL15971654 | 0.85 | MEN1 (0.74) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL29198757 | 0.85 | MEN1 (0.74) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11692049 | 0.85 | MEN1 (0.74) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11687810 | 0.85 | MEN1 (0.74) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356454-B1 | CYCLIC HYDROCARBONS WITH AN AMINOALKYL SIDECHAIN | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5001234-A | Cyclic hydrocarbons with an aminoalkyl sidechain | THE UPJOHN COMPANY (US) | 1991-03-19 | — | — | US | disclosed |