Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973017 | 0.95 | SCN9A (0.46) | KDM1ACYP2D6MEN1KMT2ACHRNB2 | |
| SCHEMBL4149119 | 0.95 | SCN9A (0.46) | KDM1ACYP2D6MEN1KMT2ACHRNB2 | |
| SCHEMBL6806512 | 0.84 | MAPT (0.41) | CYP2D6MEN1KMT2ACYP2C19POLB | |
| SCHEMBL5767274 | 0.81 | ACP3 (0.36) | CYP2D6MEN1KMT2ACYP2C19POLB | |
| Acridine SCHEMBL27871863 | 0.81 | KMT2A (0.43) | CYP2D6MEN1KMT2ACYP2C19POLB | |
| SCHEMBL2097203 | 0.80 | IDO1 (0.43) | CYP2D6MEN1KMT2ACYP2C19POLB | |
| SCHEMBL2097199 | 0.80 | MEN1 (0.41) | CYP2D6MEN1KMT2ACYP2C19POLB | |
| SCHEMBL4365261 | 0.79 | CYP2D6 (0.40) | CYP2D6CYP2C19SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL28905130 | 0.79 | NR1H4 (0.39) | CYP2D6MEN1KMT2ACHRNB2CHRNA7 | |
| Hydrochloric Acid SCHEMBL20914773 | 0.79 | CYP1A2 (0.41) | CYP2D6MEN1KMT2ACYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132459-A | Fungicides | SANDOZ LTD. (CH) | 1992-07-21 | — | — | US | disclosed |
| US-4755534-A | Propenylamines, pharmaceutical compositions containing them and their use as pharmaceuticals | SANDOZ LTD. (CH) | 1988-07-05 | — | — | US | disclosed |
| EP-0024587-B1 | PROPENYLAMINES, PROCESSES FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS PHARMACEUTICALS | SANDOZ AG (CH) | 1984-11-14 | — | — | EP | disclosed |
| EP-0024587-A1 | Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals | SANDOZ AG (CH) | 1981-03-11 | — | — | EP | disclosed |