Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 4/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963447 | 1.00 | ENPP3 (0.37) | ENPP3ENPP1FGFR1FGFR4HSD17B10 | |
| SCHEMBL966305 | 0.90 | SPR (0.30) | — | |
| SCHEMBL966304 | 0.90 | SPR (0.30) | — | |
| SCHEMBL967739 | 0.89 | IRAK4 (0.35) | FGFR1FGFR4HSD17B10 | |
| SCHEMBL964976 | 0.89 | IRAK4 (0.34) | — | |
| SCHEMBL967741 | 0.89 | IRAK4 (0.35) | FGFR1FGFR4HSD17B10 | |
| SCHEMBL964974 | 0.89 | IRAK4 (0.34) | — | |
| SCHEMBL962985 | 0.86 | POLB (0.36) | — | |
| SCHEMBL962984 | 0.86 | POLB (0.36) | — | |
| SCHEMBL962301 | 0.83 | PARP1 (0.38) | ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | PPARA, PPARD, PPARG | ENPP3 2208/4885ENPP1 1752/4885FGFR1 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.