Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.49 |
| ▸ | EIF4EBP1 | Q13541 | 4/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958209 | 0.90 | NR4A2 (0.63) | PTGDRNR4A2NR4A1NR4A3MRGPRX4 | |
| SCHEMBL960128 | 0.82 | CNR2 (0.56) | PTGDRGPR52NPC1RAB9AL3MBTL1 | |
| SCHEMBL6066388 | 0.80 | NR4A2 (0.76) | NR4A2NR4A1NR4A3MRGPRX4F10 | |
| SCHEMBL963739 | 0.80 | F10 (0.62) | GPR52F10 | |
| SCHEMBL959319 | 0.79 | MRGPRX4 (0.61) | PTGDRNR4A2NR4A1NR4A3MRGPRX4 | |
| SCHEMBL960405 | 0.77 | S1PR4 (0.45) | NR4A2NR4A1NR4A3F10NPC1 | |
| SCHEMBL960125 | 0.76 | PTGDR (0.57) | PTGDRNR4A2NR4A1NR4A3MRGPRX4 | |
| SCHEMBL958328 | 0.76 | GPR52 (0.57) | PTGDRNR4A2GPR52MRGPRX4KMO | |
| SCHEMBL958231 | 0.76 | GPR52 (0.53) | GPR52MRGPRX4KMO | |
| SCHEMBL961439 | 0.75 | GPR52 (0.52) | GPR52MRGPRX4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2253618-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | GPR4, NR3C2, NR5A2 | PTGDR 528/4885NR4A2 8/4885NR4A1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.