Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635741 | 0.89 | AURKA (0.47) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL9635679 | 0.87 | ALDH1A1 (0.48) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL9634555 | 0.85 | KDM4E (0.42) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL10741106 | 0.84 | CHRNB4 (0.40) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7272011 | 0.82 | ALOX5 (0.51) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL10850991 | 0.81 | ALOX5 (0.50) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7271663 | 0.81 | ALOX5 (0.50) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL9635683 | 0.81 | KDM4E (0.44) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL9634557 | 0.81 | KDM4E (0.52) | AURKAALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL9635746 | 0.81 | ALDH1A1 (0.44) | AURKAALDH1A1KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104881-A | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-14 | — | — | US | disclosed |
| US-4616090-A | 2-arylimidazopyridines intermediates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0072926-B1 | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GmbH (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0072926-A1 | 2-Arylimidazopyridines | MERCK PATENT GmbH (DE) | 1983-03-02 | — | — | EP | disclosed |