Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264625 | 0.92 | LMNA (0.47) | LMNATSHRL3MBTL1APEX1BLM | |
| SCHEMBL28962996 | 0.82 | TSHR (0.43) | LMNATSHRL3MBTL1APEX1BLM | |
| SCHEMBL29366012 | 0.79 | LMNA (0.40) | LMNAL3MBTL1 | |
| SCHEMBL28765225 | 0.79 | TSHR (0.41) | LMNATSHRL3MBTL1CA12CA1 | |
| SCHEMBL16203504 | 0.77 | LMNA (0.39) | LMNA | |
| SCHEMBL31733909 | 0.77 | LMNA (0.39) | LMNAL3MBTL1 | |
| SCHEMBL16135507 | 0.76 | LMNA (0.38) | LMNA | |
| SCHEMBL12337488 | 0.76 | LMNA (0.48) | LMNA | |
| SCHEMBL5558060 | 0.76 | LMNA (0.38) | LMNA | |
| SCHEMBL8178094 | 0.76 | CES1 (0.43) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169627-A | Having resistance to degradation by intestinal enzymes while retaining immunological activity | MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK (US) | 1992-12-08 | — | — | US | claimed |