Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397451 | 0.84 | CYP3A4 (0.57) | CYP3A4TP53MAPTPOLBHSP90AA1 | |
| SCHEMBL8732449 | 0.83 | ALDH1A1 (0.55) | CYP3A4TP53MAPTPOLBHSP90AA1 | |
| SCHEMBL112380 | 0.75 | CYP3A4 (1.00) | CYP3A4TP53MAPTPOLBHSP90AA1 | |
| SCHEMBL29371541 | 0.75 | CYP3A4 (1.00) | CYP3A4TP53MAPTPOLBHSP90AA1 | |
| Hydrochloric Acid SCHEMBL2871122 | 0.73 | CYP3A4 (0.96) | CYP3A4TP53MAPTPOLBHSP90AA1 | |
| Cyanide SCHEMBL27784427 | 0.71 | CYP3A4 (0.89) | CYP3A4TP53MAOBTSHRALDH1A1 | |
| SCHEMBL17781747 | 0.70 | MAOB (0.67) | CYP3A4TP53MAPTPOLBHSP90AA1 | |
| SCHEMBL8735764 | 0.70 | ALDH1A1 (0.53) | CYP3A4TP53MAPTPOLBHSP90AA1 | |
| SCHEMBL55303 | 0.69 | MAOB (0.86) | CYP3A4TP53MAPTPOLBHSP90AA1 | |
| SCHEMBL30107929 | 0.69 | MAOB (0.86) | CYP3A4TP53MAPTPOLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488630-A2 | Thermally stable polyimide and preparation process of polyimide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-06-03 | — | — | EP | disclosed |