Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9634332 | 0.99 | MEN1 (0.72) | MEN1TSHRKMT2AKDM4ETDP1 | |
| SCHEMBL10414098 | 0.92 | KDM4E (0.73) | MEN1TSHRKMT2AKDM4ETDP1 | |
| SCHEMBL2793889 | 0.84 | KMT2A (0.77) | MEN1TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL10414144 | 0.82 | KDM4E (0.61) | MEN1TSHRKMT2AKDM4ETDP1 | |
| SCHEMBL5080239 | 0.82 | KMT2A (0.78) | MEN1TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL18828716 | 0.82 | KMT2A (0.77) | MEN1TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL8916029 | 0.82 | ALDH1A1 (0.73) | MEN1TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL8920814 | 0.81 | KMT2A (0.75) | MEN1TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL26131899 | 0.80 | KEAP1 (0.59) | MEN1TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL1519223 | 0.80 | MEN1 (0.69) | MEN1TSHRKMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096900-A | Antidepressants, anxiolytic agents | SYNTHELABO (FR) | 1992-03-17 | — | — | US | disclosed |
| US-5081128-A | Antidepressants, anxiolytic agents | SYNTHELABO (FR) | 1992-01-14 | — | — | US | disclosed |