SCHEMBL9635137

SCHEMBL9635137

Brc1ccc(Br)cc1.O=[SbH]

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.73
ALDH1A1 P00352 4/20 0.50
ALOX15 P16050 2/20 0.50
MAPK1 P28482 2/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
TDP1 Q9NUW8 1/20 0.47
CA2 P00918 6/20 0.45
CA1 P00915 5/20 0.45
PLCG1 P19174 1/20 0.43
TSHR P16473 1/20 0.42
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
GSK3B P49841 1/20 0.41
CA9 Q16790 1/20 0.39
OGG1 O15527 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18508 0.85
SCHEMBL9635143 0.82 CYP2A6 (0.73) CYP2A6ALDH1A1ALOX15MAPK1CES2
Ammonia Solution, Strong SCHEMBL28776475 0.80
SCHEMBL9496102 0.80 CYP2A6 (0.89) CYP2A6ALDH1A1ALOX15MAPK1CES2
Methane SCHEMBL21489530 0.80 CYP2A6 (0.89) CYP2A6ALDH1A1ALOX15MAPK1CES2
SCHEMBL3138002 0.80
SCHEMBL21518322 0.80
SCHEMBL14245180 0.75 CYP2A6 (0.50) CYP2A6ALDH1A1ALOX15MAPK1CES2
SCHEMBL330691 0.75
SCHEMBL68094 0.73 ALDH1A1 (0.73) CYP2A6ALDH1A1ALOX15MAPK1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5118739-A Flame retardant macromolecular materials containing brominated aromatic sulfonic acid salts ETHYL CORPORATION (US) 1992-06-02 US disclosed