SCHEMBL9635144

SCHEMBL9635144

CC=COc1ccc(OC=CC)c(OCC)c1OC=CC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.33
TUBB1 Q9H4B7 2/20 0.33
ALDH1A1 P00352 4/20 0.32
KDM4E B2RXH2 4/20 0.32
TLR4 O00206 1/20 0.30
TSHR P16473 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9636247 0.92 ALDH1A1 (0.35) NQO1TUBB1ALDH1A1KDM4ETSHR
SCHEMBL29022990 0.83 GABRA1 (0.31)
SCHEMBL9634887 0.76 TSHR (0.36) NQO1TUBB1ALDH1A1KDM4ETSHR
SCHEMBL9416185 0.74 NQO1 (0.34) NQO1TUBB1ALDH1A1KDM4ETLR4
SCHEMBL8224319 0.74 ALDH1A1 (0.38) ALDH1A1TSHRMAPT
SCHEMBL5611836 0.73 SMN1; SMN2 (0.31)
SCHEMBL15722967 0.72 FGFR2 (0.34) TUBB1ALDH1A1KDM4EGAAMAPT
SCHEMBL9196941 0.71 ALDH1A1 (0.48) NQO1TUBB1ALDH1A1KDM4ETSHR
SCHEMBL9619092 0.67 ALDH1A1 (0.36) NQO1TUBB1ALDH1A1KDM4ETSHR
SCHEMBL15722947 0.66 NQO1 (0.40) NQO1ALDH1A1KDM4ETSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102966-A Addition polymerization of unsaturated ethers using an unsaturated alkenyl polyether adduct as initiator and a cation-donating compound SEKISUI CHEMICAL CO., LTD. (JP) 1992-04-07 US disclosed