Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 7/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636164 | 0.90 | KCNH2 (0.45) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10648280 | 0.89 | LMNA (0.44) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9636218 | 0.89 | ALDH1A1 (0.41) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10509964 | 0.89 | TOP2A (0.44) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9671115 | 0.88 | ALDH1A1 (0.46) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10589657 | 0.87 | ALDH1A1 (0.38) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8435557 | 0.87 | ALDH1A1 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10647453 | 0.87 | ALDH1A1 (0.40) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10646491 | 0.87 | ALDH1A1 (0.47) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9634817 | 0.87 | KCNH2 (0.40) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337231-B1 | I. M. INJECTION FORMS OF GYRASE-INHIBITORS | BAYER AG (DE) | 1992-06-17 | — | — | EP | disclosed |
| EP-0274033-B1 | PROCESS FOR THE PREPARATION OF QUINOLINECARBOXYLIC ACIDS | BAYER AG (DE) | 1992-03-11 | — | — | EP | disclosed |
| EP-0167763-B1 | 7-AMINO-1-CYCLOPROPYL-6,8-DIHALO-1,4-DIHYDRO-4-OXO-3-QUINOLINE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND BACTERICIDAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |
| EP-0274033-A1 | Process for the preparation of quinolinecarboxylic acids | BAYER AG (DE) | 1988-07-13 | — | — | EP | disclosed |
| EP-0167763-A1 | 7-Amino-1-cyclopropyl-6,8-dihalo-1,4-dihydro-4-oxo-3-quinoline-carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0164619-A1 | 2,4,5-Trihalo or 2,3,4,5-tetrahalo benzene derivatives and process for producing them | BAYER AG (DE) | 1985-12-18 | — | — | EP | disclosed |