Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635286 | 0.74 | RYR2 (0.51) | RYR2PRKD1CDK1MAPKAPK2HSP90AA1 | |
| SCHEMBL9635203 | 0.73 | PARP10 (0.42) | RYR2PRKD1PRKD2PRKD3CDK1 | |
| SCHEMBL9635219 | 0.67 | PARP10 (0.42) | RYR2PRKD1PRKD2PRKD3CDK1 | |
| SCHEMBL28443875 | 0.67 | RYR2 (0.43) | RYR2PRKD1PRKD2PRKD3CDK1 | |
| SCHEMBL9040253 | 0.65 | RYR2 (0.44) | RYR2PRKD1PRKD2PRKD3CDK1 | |
| SCHEMBL2600209 | 0.64 | RYR2 (0.66) | RYR2PARP10PARP11PARP1LMNA | |
| SCHEMBL9635151 | 0.64 | PARP10 (0.50) | RYR2PARP10PARP11PARP1F7 | |
| SCHEMBL26942243 | 0.64 | PARP10 (0.54) | RYR2PRKD1CDK1MAPKAPK2PARP10 | |
| SCHEMBL15471838 | 0.61 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL13092712 | 0.60 | PARP10 (0.42) | PARP10PARP11PARP1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0368063-A1 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |