Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11229294 | 0.98 | HTR6 (0.43) | HTR6GBA1HTR2CSLC6A4SLC6A2 | |
| SCHEMBL11228466 | 0.87 | HTR6 (0.42) | HTR6GBA1HTR2CSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL11235358 | 0.86 | HTR6 (0.41) | HTR6GBA1HTR2CSLC6A4SLC6A2 | |
| SCHEMBL11220649 | 0.84 | SLC6A4 (0.41) | HTR6GBA1HTR2CSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL11227056 | 0.83 | SLC6A4 (0.40) | HTR6GBA1HTR2CSLC6A4SLC6A2 | |
| SCHEMBL28192895 | 0.83 | HTR6 (0.46) | HTR6SIGMAR1 | |
| SCHEMBL1453509 | 0.78 | HTR6 (0.58) | HTR6HTR2CSLC6A2SLC6A3KCNH2 | |
| SCHEMBL11232648 | 0.76 | NAMPT (0.41) | HTR6SLC6A4 | |
| SCHEMBL9859810 | 0.76 | HTR6 (0.56) | HTR6HTR2CSLC6A2SLC6A3KCNH2 | |
| SCHEMBL3443376 | 0.72 | HTR6 (0.53) | HTR6HTR2CSLC6A2SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |