Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11227056 | 0.99 | SLC6A4 (0.40) | SLC6A4HTR6GBA1NAMPTKDM1A | |
| SCHEMBL11228466 | 0.91 | HTR6 (0.42) | SLC6A4HTR6GBA1KDM1AMAOA | |
| SCHEMBL11232648 | 0.90 | NAMPT (0.41) | SLC6A4HTR6NAMPT | |
| Hydrochloric Acid SCHEMBL11235358 | 0.90 | HTR6 (0.41) | SLC6A4HTR6GBA1KDM1AMAOA | |
| SCHEMBL9635266 | 0.84 | HTR6 (0.44) | SLC6A4HTR6GBA1KDM1AMAOA | |
| Hydrochloric Acid SCHEMBL11229294 | 0.83 | HTR6 (0.43) | SLC6A4HTR6GBA1KDM1AHTR2C | |
| SCHEMBL1949777 | 0.82 | HTR6 (0.53) | HTR6HTR2CSLC6A2SLC6A3 | |
| SCHEMBL6673091 | 0.79 | HTR6 (0.53) | HTR6HTR2CSLC6A2SLC6A3 | |
| SCHEMBL6675770 | 0.77 | HTR6 (0.51) | HTR6HTR2CSLC6A2SLC6A3 | |
| SCHEMBL6675371 | 0.77 | HTR6 (0.51) | HTR6HTR2CSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |