Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.50 |
| ▸ | RXRB | P28702 | 6/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636818 | 0.94 | TSHR (0.48) | RXRARXRBRXRGCA12CA1 | |
| SCHEMBL9618138 | 0.79 | MAPT (0.42) | KMT2A | |
| SCHEMBL2627825 | 0.79 | RXRA (0.68) | RXRARXRBRXRGGRIA4BCL2L1 | |
| SCHEMBL8833495 | 0.77 | TSHR (0.50) | RXRARXRBRXRGCA12CA1 | |
| SCHEMBL9330598 | 0.77 | RXRA (0.56) | RXRARXRBRXRGGRIA4BCL2L1 | |
| SCHEMBL9636806 | 0.77 | RXRA (0.46) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL11877213 | 0.75 | TSHR (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL10900089 | 0.75 | TSHR (0.52) | CA12CA1CA2CA9CA14 | |
| Acrylic Acid SCHEMBL28859858 | 0.74 | BCL2L1 (0.58) | RXRARXRBRXRGBCL2L1BAD | |
| SCHEMBL2009011 | 0.74 | TP53 (0.46) | RXRARXRBRXRGCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283326-B1 | LIQUID CRYSTAL COMPOUNDS WITH 4-(OPTICALLY ACTIVE ALKYL)-3-CYANOPHENYL GROUPS | Chisso Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-4913838-A | LARGE SPONTANEOUS POLARIZATION VALUE | CHISSO CORPORATION (JP) | 1990-04-03 | — | — | US | disclosed |