SCHEMBL9635281

SCHEMBL9635281

CSC1=Nc2ccccc2[S+]([O-])C1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.31
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
GSK3B P49841 1/20 0.31
CCNB3 Q8WWL7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9635288 0.83
SCHEMBL9635208 0.81
SCHEMBL9635210 0.81
SCHEMBL10026452 0.64 HRH4 (0.40) CCNB2CDK1CCNB1GSK3BCCNB3
SCHEMBL11478657 0.63 NOS3 (0.52) CCNB2CDK1CCNB1GSK3BCCNB3
SCHEMBL692287 0.61 NOS3 (0.44) CCNB2CDK1CCNB1GSK3BCCNB3
SCHEMBL7458656 0.61 OPRK1 (0.37) CCNB2CDK1CCNB1GSK3BCCNB3
SCHEMBL11406516 0.60 CCNB2 (0.45) CCNB2CDK1CCNB1GSK3BCCNB3
SCHEMBL11628607 0.60 MAPT (0.45)
SCHEMBL17058245 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0368063-B1 PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS BAYER AG (DE) 1992-06-10 EP disclosed
US-4990707-A Process for the ring chlorination of aromatic hydrocarbons BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
EP-0368063-A1 Process for the chlorination in the nucleus of aromatic hydrocarbons BAYER AG (DE) 1990-05-16 EP disclosed