Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872029 | 0.86 | L3MBTL1 (0.65) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL7147305 | 0.86 | L3MBTL1 (0.56) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL13177349 | 0.81 | USP30 (0.62) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL1055082 | 0.81 | USP30 (0.62) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL853539 | 0.81 | USP30 (0.62) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL853540 | 0.81 | USP30 (0.62) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL14037432 | 0.81 | USP30 (0.62) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL1545229 | 0.79 | L3MBTL1 (0.74) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL14022760 | 0.79 | L3MBTL1 (0.74) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL8263564 | 0.79 | L3MBTL1 (0.74) | ALDH1A1L3MBTL1ATMCCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5084572-A | Cardiovascular disorders | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991007405-A1 | SALTS OF 3-AZABICYCLO[3.3.1]NONANES AS ANTIARRHYTHMIC AGENTS, AND PRECURSORS THEREOF | THE BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1991-05-30 | — | — | WO | disclosed |