Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872029 | 0.88 | L3MBTL1 (0.65) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL6749184 | 0.86 | S1PR5 (0.50) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL9635294 | 0.86 | ALDH1A1 (0.57) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL14037432 | 0.82 | USP30 (0.62) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL13177349 | 0.82 | USP30 (0.62) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL853540 | 0.82 | USP30 (0.62) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL1055082 | 0.82 | USP30 (0.62) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL853539 | 0.82 | USP30 (0.62) | L3MBTL1ATMALDH1A1CCR8KDM4E | |
| SCHEMBL6745182 | 0.82 | S1PR5 (0.65) | L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1545229 | 0.80 | L3MBTL1 (0.74) | L3MBTL1ATMALDH1A1CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5084572-A | Cardiovascular disorders | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-01-28 | — | — | US | disclosed |