Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920426 | 0.81 | — | — | |
| SCHEMBL21217022 | 0.76 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22039176 | 0.76 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10963502 | 0.73 | TBXAS1 (0.41) | PLA2G1BPLA2G2ADNM1CYP1A2CYP2D6 | |
| SCHEMBL9533443 | 0.73 | CYP2C19 (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7811093 | 0.73 | CYP2C19 (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24862654 | 0.67 | CYP2C19 (0.36) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20981285 | 0.64 | CYP19A1 (0.38) | CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19347168 | 0.64 | KCNH2 (0.36) | DNM1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9584228 | 0.64 | LMNA (0.38) | CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118702-A | FUNGICIDAL AND MICROBICIDAL SUBSTITUTED 1-AMINOMETHYL-3-ARYL-4-CYANO-PYRROLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| EP-0435043-A1 | Substituted 1-aminomethyl-3-aryl-4-cyano-pyrroles | BAYER AG (DE) | 1991-07-03 | — | — | EP | disclosed |
| EP-0106243-B1 | AZOLYL-METHYL AMINES, THEIR PREPARATION AND THEIR USE IN MICROBICIDE COMPOSITIONS | BAYER AG (DE) | 1986-05-28 | — | — | EP | disclosed |
| EP-0106243-A1 | Azolyl-methyl amines, their preparation and their use in microbicide compositions | BAYER AG (DE) | 1984-04-25 | — | — | EP | disclosed |